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      <image:title>Sanders Lab of Molecular Networks - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
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      <image:title>Publications - (18) Condensate interfaces can accelerate protein aggregation</image:title>
      <image:caption>C-H Choi, DSW Lee, DW Sanders, CP Brangwynne Biophysical Journal (2023) [PDF] [Preview by Samrat Mukhopadhyay]</image:caption>
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      <image:title>Publications - (17) Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions</image:title>
      <image:caption>J Park, Y Wu, W Shao, TF Gendron, SJF van der Spek, G Sultanakhmetov, A Basu, PC Otero, CJ Jones, K Jansen-West, LM Daughrity, S Phanse, G del Rosso, J Tong, M Castanedes-Casey, L Jiang, J Libera, B Oskarsson, DW Dickson, DW Sanders, CP Brangwynne, A Emili, B Wolozin, L Petrucelli, YJ Zhang Cell Reports (2023) [PDF]</image:caption>
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      <image:title>Publications - (16) Size distributions of intracellular condensates reflect competition between coalescence and nucleation</image:title>
      <image:caption>DSW Lee, CH Choi, DW Sanders, L Beckers, JA Riback, CP Brangwynne, NS Wingreen Nature Physics (2023) Biorxiv (Pre-print, Mar. 2022) [PDF] [Princeton Press Release]</image:caption>
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      <image:title>Publications - (15) SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation</image:title>
      <image:caption>DW Sanders*, CC Jumper*, PJ Ackerman*, D Bracha, A Donlic, H Kim, D Kenney, S Suzuki, T Tamura, I Castello-Serrano, AH Tavares, M Saeed, AS Holehouse, A Ploss, I Levental, F Douam, RF Padera, BD Levy, CP Brangwynne eLife (2021) Biorxiv (Pre-Print, Dec. 2020) [PDF-Main] [PDF-Supp] [HHMI News Story] [Presentation by Cliff] [THE Medical News Article] [Speak Russian? David doesn’t. But Grisha does]</image:caption>
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      <image:title>Publications - (14) Nucleation landscape of biomolecular condensates</image:title>
      <image:caption>SF Shimobayashi, P Ronceray, DW Sanders, MP Haataja, CP Brangwynne Nature (2021) [PDF] [Princeton Press Release]</image:caption>
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      <image:title>Publications - (13) Competing protein-RNA interaction networks control multiphase intracellular organization</image:title>
      <image:caption>DW Sanders, N Kedersha, DSW Lee, AR Strom, V Drake, JA Riback, D Bracha, JM Eeftens, A Iwanicki, A Wang, MT Wei, G Whitney, SM Lyons, P Anderson, WM Jacobs, P Ivanov, CP Brangwynne Cell (2020) [PDF-Main] [PDF-Supp] [Preview By Ashok Deniz] [Princeton Press Release] [Princeton Insights Coverage] [Fist-Bump from Mike Rosen in Science ] [Nature News-Building Out]</image:caption>
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      <image:title>Publications - (12) Composition dependent thermodynamics of intracellular phase separation</image:title>
      <image:caption>JA Riback, L Zhu, MC Ferrolino, M Tolbert, DM Mitrea, DW Sanders, MT Wei, RW Kriwacki, CP Brangwynne Nature (2020) . [PDF] [Preview By Chiu Fan Lee] [Princeton Press Release]</image:caption>
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      <image:title>Publications - (11) Liquid nuclear condensates mechanically sense and restructure the genome</image:title>
      <image:caption>Y Shin, YC Chang, DSW Lee, J Berry, DW Sanders, P Ronceray, NS Wingreen, M Haataja, CP Brangwynne Cell (2018) [PDF] [Preview By Tuomas Knowles] [Nature Methods Overview] [Princeton Press Release]</image:caption>
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      <image:title>Publications - (10) COMMENTARY: Neurodegenerative disease: RNA repeats put a freeze on cells</image:title>
      <image:caption>DW Sanders &amp; CP Brangwynne Nature (2017) [PDF] See original paper from Jain &amp;Vale!</image:caption>
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      <image:title>Publications - (9) DNAJC7 specifically regulates tau seeding</image:title>
      <image:caption>VA Perez, DW Sanders, A Mendoza-Oliva, BE Stopschinski, V Mullapudi, CL White, LA Joachimiak, MI Diamond eLife (2023) Biorxiv (Pre-print, Mar 2023) [PDF]</image:caption>
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    <image:image>
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      <image:title>Publications - (8) The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system</image:title>
      <image:caption>I Saha, P Yuste-Checa, M Da Silva Padilha, Q Guo, R Körner, H Holthusen, VA Trinkaus, I Dudanova, R Fernández-Busnadiego, W Baumeister, DW Sanders, S Gautam, MI Diamond, FU Hartl, MS Hipp Nature Communications (2023) Biorxiv (Pre-print, Feb 2022) [PDF]</image:caption>
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      <image:title>Publications - (7) The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition</image:title>
      <image:caption>G Eskandari-Sedighi, N Daude, H Gapeshina, DW Sanders, R Kamali-Jamil, J Yang, B Shi, H Wille, B Ghetti, MI Diamond, C Janus, D Westaway Molecular Neurodegeneration (2017) [PDF]</image:caption>
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      <image:title>Publications - (6) Tau prion strains dictate patterns of cell pathology, progression rate, and regional vulnerability in vivo</image:title>
      <image:caption>SK Kaufman*, DW Sanders*, TL Thomas, AJ Ruchinskas, J Vaquer-Alicea, AM Sharma, TM Miller, MI Diamond Neuron (2016) [PDF] [UT Southwestern Press Release] [AlzForum Coverage]</image:caption>
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      <image:title>Publications - (5) Neuronal activity enhances tau propagation and tau pathology in vivo</image:title>
      <image:caption>JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, DW Sanders, C Cook, H Fu, RACM Boonen, M Herman, E Nahmani, S Emrani, YH Figueroa, MI Diamond, CL Clelland, S Wray, KE Duff Nature Neuroscience (2016) [PDF] [Columbia Press Release] [AlzForum Coverage]</image:caption>
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      <image:title>Publications - (4) REVIEW: Prions and protein assemblies that convey biological information in health and disease</image:title>
      <image:caption>DW Sanders*, SK Kaufman*, BB Holmes*, MI Diamond Neuron (2016) [PDF]</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/1609373079760-RUZDRJUA7NKUZNHUJM68/Prusiner_IMG.png</image:loc>
      <image:title>Publications - (3) Propagation of prions causing synucleinopathies in cultured cells</image:title>
      <image:caption>AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, T Ohyama, S Patel, K Widjaja, A Oehler, DW Sanders, MI Diamond, WW Seeley, LT Middleton, SM Gentleman, DA Mordes, TC Südhof, K Giles, SB Prusiner PNAS (2015) [PDF]</image:caption>
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      <image:title>Publications - (2) Tau trimers are the minimal propagation unit spontaneously internalized to seed intracellular aggregation</image:title>
      <image:caption>H Mirbaha, BB Holmes, DW Sanders, J Bieschke, MI Diamond Journal of Biological Chemistry (2015) [PDF] [Alzforum Coverage]</image:caption>
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      <image:title>Publications - (1) Distinct tau prion strains propagate in cells and mice and define different tauopathies.</image:title>
      <image:caption>DW Sanders*, SK Kaufman*, SL DeVos, AM Sharma, H Mirbaha, A Li, SJ Barker, AC Foley, JR Thorpe, LC Serpell, TM Miller, LT Grinberg, WW Seeley, MI Diamond Neuron (2014) [PDF] [Preview by Brad Hyman] [WashU Press Release] [AlzForum Coverage of Paper] [AlzForum Coverage of Prelim Data]﻿</image:caption>
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    <lastmod>2026-06-18</lastmod>
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      <image:title>News - June 8, 2026: After months of recruitment efforts, Alvin signed the paperwork! He is now officially a Shahmorander! Sarah and David are thrilled to mentor him on his membrane-centric explorations of unknown scientific frontiers! Destroy, destroy!</image:title>
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      <image:title>News - June 1, 2026: Another summer, another batch of highly influenced Shahmorander Youth Achievers (TM). This time, we welcome three new shining beacons on our flat plane: (A) Ishita Vats (left, Plano Eastside High—probably), shown in her natural habitat of a science museum; (B) Krish Khosla (middle), displayed being way too serious for his own good at UT Austin; and (C) Romena Alladin (right), not shown as she has yet to send the webmasters a photo/blurb from her busy, yet-to-be TikTaked times at UT Austin! Welcome to the lab y’all, be on good (enough) behavior, and don’t cure too many diseases. Leave some scraps for us old folk! We’ve tried nothing but are all out of ideas!</image:title>
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      <image:title>News - May 22, 2026: Haoxing passed his qualifying exam! But was left incapacitated by the so-called “patented system” of his chair, Vinni Tagliabracci. Heck of a system you have there, Vinni. Sure, Haoxing passed, but at what cost? Disclaimer: a legal settlement was reached that requires the following text is posted: the Vinni Tagliabracci system remains patent pending and takes zero responsibility for the permanent maiming of trainees who cannot handle its unrivaled rigor.</image:title>
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      <image:title>News - April 30, 2026: It was sad to say goodbye to both Sherry Clark (left) and Dana Dood (right), both of which overlapped with Dr. David in Marc Diamond’s lab in his younger and more vulnerable years. As he is a class act, Marc (Center director) gave an unrivaled sendoff. We envy his oration abilities!</image:title>
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      <image:title>News - April 24, 2026: Tak ate at the RNA symposium but wasn’t done feeding. He insisted on a second mic drop of the polyserine story at the CMB symposium THE VERY NEXT DAY! Strong power move, Tak. Strong. FEED!!!</image:title>
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      <image:title>News - April 23, 2026: The Shahmoranders know all, tell most: explains why the ravenous masses demanded TWO selected talks from their horde to lay waste to competitors at the annal UTSW RNA Symposium. Kinda sad that more established HHMI labs can’t compete. But they are what they are. Way to go Tak and Shefali!</image:title>
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      <image:title>News - April 17, 2026: Thank you to Mike Henne for hosting Cell Editor extraordinaire, Antonia de Maio, for a visit to UT Southwestern, and for being magnanimous enough to allow Sarah and David (AND geranyl-geranylation guru, Pete Douglas) for a fine dinner at the seafood place that blocks traffic at David’s orthodontist. Straight teeth speak straight truths!</image:title>
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      <image:title>News - April 15, 2026: Another hosted speaker, another Uchi Omakase experience! This time with Vik Khurana. David and Vik bonded over their shared experiences in Alice Springs, Australia, one of which was lived, the other of which was gleaned from Wikipedia while some idiot wore a silly cowboy hat. Sarah engaged in more substantial conversations about alpha synuclein. Peter Douglas joined. There was certainly discussion about geranyl-geranylation. Because, it is all.</image:title>
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      <image:title>News - March 5, 2026: Lab achievement unlocked! Yogesh Tak receives our FIRST trainee-initiated funding for his work on polyanionic cofactors in tau fibril toxicity. It’s a Sprouts grant, so we expect the greenest shoots possible to burst forth from his coffers!</image:title>
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      <image:title>News - January 5, 2026: We are excited to host Alvin Wang for a rotation in the Shahmoranders Lab! He will be leading live cell imaging efforts to understand how aSyn fibrils engage organelles in living cells!</image:title>
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      <image:title>News - December 17, 2025: Sarah and David greatly enjoyed hosting Aaron Gitler (Stanford), who gave an excellent talk on EVERYTHING with a focus on his latest TMEM106B findings! A fantastic dinner was had at Uchi. Omakase, clearly. Regina joined, as always.</image:title>
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      <image:title>News - November 25, 2025: Yogesh Tak officially joins the lab as an joint lab member with Marc Diamond, having spent two years polishing his biochemistry chops in Diamond’s lab. He has been assigned the unenviable task of breaking the wretched polyserine curse that has taken down so many of us mere mortals. Pray for him! The road is paved with the dead that took on the polyserine meatgrinder…</image:title>
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      <image:title>News - October 20, 2025: We are excited to welcome Noah Haggerty to the lab as its second rotation student of the year! Noah will be working with Tak on the very exciting and DEFINITELY NOT CURSED polyserine project. Noah will soon learn that the project is almost certainly cursed.</image:title>
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      <image:title>News - October 8, 2025: the embargo has been lifted! We are pleased to announce that one of our dear leaders, Dr. David, has been selected as one of 29-early career investigators in the whole US of A for a New Innovator Award. This honor is bestowed upon those who present highly creative approaches for solving big questions with major public health relevance. David is humbled to accept this incredibly helpful influx of $$$ and….a bit of prestige? Thank you to UT Southwestern for the amazing press coverage: https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-nih-directors-new-innovator-award.html David specifically thanks the NIH’s civil servants for their hard work during a stressful funding cycle. He also thanks the leadership (and chair, Marc Diamond) at UTSW for betting on the lab’s high risk, high reward research, and of course, the even-greater innovator, Sarah Shahmoradian, who co-leads the lab! More info on this excellent funding mechanism: https://www.nih.gov/common-fund/common-fund-programs/high-risk-high-reward-research-hrhr/nih-directors-new-innovator-award</image:title>
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      <image:title>News - October 4, 2025: Another year, another Center Diwali. Thank you, Tak (not shown) and friends for hosting a fantastic party! Thanks to David for opening the last bottle of wine with a rock. Truely deserving of a New Innovator Award, methinks?</image:title>
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      <image:title>News - October 1, 2025: We are thrilled to announce that Burak Okumus has joined the Shahmoranders as a Senior Scientist. Burak is a methods genius and tinkerer, who has spent decades refining the dark arts of microfabrication and single-molecule techniques. He will be working on whatever he feels like, gosh-darn-it! As he should! First step: buy 3D printer.</image:title>
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      <image:title>News - September 1, 2025: The lab welcomes Weiren Wang as a Fall rotation student! Weiren will be working with Shefali on a pilot project regarding the organization of titin mRNPs in cultured skeletal muscle!</image:title>
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      <image:title>News - August 18, 2025: The lab welcomes its latest member, Emma Choo, who is joining the group as a Data Scientist! She will be crunching some tomograms with the help of artificial intelligence, if AI is truly as smart as it claims to be!</image:title>
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      <image:title>News - August 13, 2025: Sarah and David present their joint research to grad students at “Please Join Our Lab” Day. Several students entertained their wild ramblings. Will such rubberneckers rotate? They will. Obviously. But, stay tuned!</image:title>
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      <image:title>News - August 11, 2025: A Sasquatch invades the thesis celebration of good friend of the lab, Peter Kunach. Congratulations Peter on your thesis! And your samsquanch discovery…</image:title>
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      <image:title>News - August 8, 2025: The lab celebrated both Jenny and Sarah’s birthdays the best way they knew how: By stabbing things!</image:title>
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      <image:title>News - July 29, 2025: Within moments of discovering John’s re-furbished mass spectrometer, David effortlessly masters it. With the help of shooting range hearing protection, clearly. Keep those ears safe kids from the….peptides.</image:title>
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  </url>
  <url>
    <loc>https://www.davidwsanders.com/news-2</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2026-06-17</lastmod>
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      <image:title>News (2024) - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/529efd73-7e26-49ac-8efc-ad78e41a4681/Screenshot+2024-10-12+at+5.11.21%E2%80%AFPM.jpg</image:loc>
      <image:title>News (2024) - October 4, 2024: Genentech, inventor of proteins, received the David Sanders seminar experience. A new lab enemy was made: that damn biotech-bro security robot. Never…ever….trust….robots!</image:title>
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      <image:title>News (2024) - May 31, 2024: The entire lab is THRILLED to learn that Vaibhav Bommareddy will be joining the lab for his MD/PhD studies. David is personally humbled that such a remarkable young scientist would join his (new/untested) group.</image:title>
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      <image:title>News (2024) - April 14, 2024: The lab took its first group outing to some weird reptile/bug convention thing. While most lab members (reasonably) posed with snakes, sloths, and other cool breathing beasts, David spent the afternoon looking for weird bugs and sickly frogs. He bought some. EDIT: They were all eaten by maggots. Circle of academia….I mean, life.</image:title>
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      <image:title>News (2024) - April 8, 2024: The sky got black because some stupid moon thing got in the way of the sun. So. The lab took the day off and trusted the integrity of our future eyesights to free eclipse glasses that were manufactured by an unknown vendor in an unknown country. We’re near a hospital. Sure it’s fine.</image:title>
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      <image:title>News (2024) - April 5, 2024: First Sanders Lab meeting. The most exciting one: discussion of database organization. Very metal! Next on agenda? Cure the diseases. First up: all of them. All. Guessing…boron (?)…is the answer? Certainly boron. Not manganese, that’s for sure. Still on my element shit list.</image:title>
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      <image:title>News (2024)</image:title>
      <image:caption>April 3, 2024: Today, we welcome our latest postdoctoral fellow, Rupam Ghosh, who abandoned the cash-laden fields of the consulting world to return to the academic fold. Rupam received a PhD from UT Southwestern, so is well versed in our unbreakable bureaucracy! Texas may love freedom, but not when it comes to paperwork!</image:caption>
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      <image:title>News (2024) - April 2, 2024: Big day for the lab. Baby mantid’s first molt! They grow up so fast! …New PI priorities. Time spent writing grants to date: 1 hour. Time spent attending to lab pet (mantis colony): 50 hours. No regrets.</image:title>
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      <image:title>News (2024) - March 31, 2024: Getting bigger! First molt soon! Still have 80+ survivors at Day 10. But guessing the crowded enclosure will cause mantids to climb over those molting and lead to rampant failed instar progressions.</image:title>
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      <image:title>News (2024) - March 21, 2024: The Sanders lab has hundreds of mantids. Be afraid. Be very afraid! Video for the fans: https://x.com/DavidWSanders2/status/1770927008123429165</image:title>
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      <image:title>News (2024) - March 8, 2024: We are equally excited to share that the lab’s second postdoctoral fellow, Yasmeen Khan, has arrived! David enjoyed giving her a tour of the lab space today. She will officially start on Monday, planning to lead work on RNA homeostasis in the cytoplasm. Narrator: how did that transition to lysosome homeostasis?</image:title>
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      <image:title>News (2024) - March 4, 2024: We are excited to announce that the lab’s first postdoctoral fellow, Grigorii (Grisha) Sultanakhmetov, has officially started! He will be working on TDP aggregation and whatever else he gets excited about tomorrow. Welcome to the lab, Grisha!</image:title>
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      <image:title>News (2024)</image:title>
      <image:caption>February 16, 2024: David enjoyed giving a flash talk to students who have been accepted into the graduate programs at UT Southwestern. He hopes that they find their visitation weekends as magical as he did when he was in their shoes!</image:caption>
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      <image:title>News (2024)</image:title>
      <image:caption>February 15, 2024: Our lab space has unexpectedly become a hot spot to shoot promo commercials for UT Southwestern. Have a passion for science AND want to add a credit to your IMDB profile? Join the Sanders Lab. Where stars are born!</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/75544f8a-823a-4f4f-9d18-699a83bf78a8/New_PI_Happy_Hour.jpg</image:loc>
      <image:title>News (2024)</image:title>
      <image:caption>February 7, 2024: David enjoyed attending the first UT Southwestern New PI Happy Hour! It was wonderful to meet so many excellent new colleagues. Thank you to Ashley Solmonson and Frankie Heyward for organizing!</image:caption>
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      <image:title>News (2024) - January 27, 2024: Vaibhav DESTROYS his first MSTP module final exam and takes advantage of the sumptuous desks of the lab to take a much deserved nap. Way to go, Vaibhav!</image:title>
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      <image:title>News (2024) - January 25, 2024: Team Nikon installs the Sanders Lab’s first microscope, a CSU-W1 SoRa, ahead of schedule. The lab quickly crushes the diffraction limit using a classic cell line created by David in 2012 (DS9 tau aggregate HEK293 cells)! https://x.com/DavidWSanders2/status/1750928003796799582?s=20</image:title>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/135da5c8-fb34-49ec-9fb1-38d287c9eca0/Vaibhav_JPG.jpg</image:loc>
      <image:title>News (2024) - January 2, 2024: The Sanders Lab welcomes its first rotation student, Vaibhav Bommareddy, who journeys far from the mystical land of the medical scientist training program (MSTP) at UT Southwestern. He embraces the challenge of tackling both bench work and a daunting regimen of med school classes simultaneously. Pray for Vaibhav!</image:title>
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      <image:title>News (2024)</image:title>
      <image:caption>December 1, 2023: We are excited to welcome our first research scientist, Michael Jimenez, to the lab! Michael did his undergraduate studies at Texas A&amp;M and hopes to learn everything he can about molecular biology. David can’t wait to teach this electrical engineer a bit about the messiness of cell biology.</image:caption>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/78769472-c6d1-4be2-9e4a-86ce312da6e9/Boxes.jpg</image:loc>
      <image:title>News (2024)</image:title>
      <image:caption>November 7, 2023: First packages have arrived! And we inherited our first piece of barely functional lab equipment! This item, a centrifuge of uncertain place and time, requires a three-step process to open. Fail? It chides the user with a loud "incorrect answer" buzz. Further, the user must slam the lid for it to close. Clearly, David is in love with this weathered machine. For he is a weathered machine.</image:caption>
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      <image:title>News (2024) - November 1, 2023: The Sanders lab officially opens in the Center for Alzheimer’s and Neurodegenerative Diseases at UT Southwestern! David conquers Taleo training modules at unprecedented rates using multiple browsers! An intimidating number of orders are placed. Pictures are had.</image:title>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/8fe990cb-20f1-4530-9a82-0c0219c3e596/Arrival_1.jpeg</image:loc>
      <image:title>News (2024) - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5e3f08380b0aed2f275d04bb/6dd9146b-46ba-43a9-974a-a98e88aab7cf/David_Mel.jpg</image:loc>
      <image:title>News (2024) - July 14, 2023: David is excited to announce that the Sanders Lab will launch in November 2023 at UT Southwestern (primary appointment: Center for Alzheimer’s and Neurodegenerative Diseases; secondary appointments: Molecular Biology and the O’Donnell Brain Institute). We will pursue curiosity-driven science related to RNA-protein assemblies and diseases of aging! Please reach out if your favorite papers start with a mistake, following a serendipitous observation into the unknown. We will be hiring fearless iconoclasts at all levels! Special thanks to David’s partner, Mel (pictured), who is uprooting her life in New Jersey to join him in Dallas, Texas!</image:title>
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  </url>
  <url>
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    <lastmod>2026-06-18</lastmod>
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      <image:title>News (2025) - December 17, 2025: Sarah and David greatly enjoyed hosting Aaron Gitler (Stanford), who gave an excellent talk on EVERYTHING EVER with a focus on his latest TMEM106B findings! A fantastic dinner was had at Uchi. Omakase, clearly. Regina joined, as always.</image:title>
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      <image:title>News (2025) - November 25, 2025: Yogesh Tak officially joins the lab as an honorary joint lab member, having spent two years polishing his biochemistry chops in Marc Diamond’s lab. He has been assigned the unenviable task of breaking the wretched polyserine curse that has taken down so many mere mortals. Pray for him!</image:title>
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      <image:title>News (2025) - October 20, 2025: We are excited to welcome Noah Haggerty to the lab as its second rotation student of the year! Noah will be working with Tak on the very exciting and DEFINITELY NOT CURSED polyserine project. Noah will soon learn that the project is almost certainly cursed.</image:title>
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      <image:title>News (2025) - October 8, 2025: the embargo has been lifted! We are pleased to announce that one of our dear leaders, Dr. David, has been selected as one of 29-early career investigators in the whole US of A for a New Innovator Award. This honor is bestowed upon those who present highly creative approaches for solving big questions with major public health relevance. David is humbled to accept this incredibly helpful influx of $$$ and….prestige? Thank you to UT Southwestern for the amazing press coverage: https://www.utsouthwestern.edu/newsroom/articles/year-2025/oct-nih-directors-new-innovator-award.html David specifically thanks the NIH’s civil servants for their hard work during a stressful funding cycle. He also thanks the leadership (and chair, Marc Diamond) at UTSW for betting on his high risk, high reward research and of course, the even greater innovator, Sarah Shahmoradian, who co-leads the lab! More info on this excellent funding mechanism: https://www.nih.gov/common-fund/common-fund-programs/high-risk-high-reward-research-hrhr/nih-directors-new-innovator-award</image:title>
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      <image:title>News (2025) - October 4, 2025: Another year, another Center Diwali. Thanks Tak (not shown) and friends for hosting a fantastic party! Thanks to David for opening the last bottle of wine with a rock. Truely deserving of a New Innovator award, methinks?</image:title>
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      <image:title>News (2025) - October 1, 2025: We are thrilled to announce that Burak Okumus has joined the Shahmoranders as a Senior Scientist. Burak is a methods genius and tinkerer, who has spent decades refining the dark arts of microfabrication and single-molecule techniques. He will be working on whatever he feels like, gosh-darn-it! As he should! First step: buy 3D printer.</image:title>
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      <image:title>News (2025) - September 1, 2025: The lab welcomes Weiren Wang as a Fall rotation student! Weiren will be working with Shefali on a pilot project to study the organization of titan mRNPs in cultured skeletal muscle!</image:title>
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      <image:title>News (2025) - August 18, 2025: The lab welcomes its latest member, Emma Choo, who is joining the group as a Data Scientist! She will be crunching some tomograms with the help of artificial intelligence, if it truly is as smart as it claims to be!</image:title>
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      <image:title>News (2025) - August 13, 2025: Sarah and David present their joint research to grad students at “please join our lab” day. Several students entertained their ramblings. Will they rotate? Stay tuned!</image:title>
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      <image:title>News (2025) - August 11, 2025: A Sasquatch invades the thesis celebration of good friend of the lab, Peter Kunach. Congratulations Peter on your thesis! And your samsquanch discovery…</image:title>
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      <image:title>News (2025) - August 8, 2025: The lab celebrated both Jenny and Sarah’s birthdays the best way they knew how: By stabbing at things!</image:title>
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      <image:title>News (2025) - July 29, 2025: Within moments of discovering John’s re-furbished man spectrometer, David effortlessly masters it. With the help of shooting range hearing protection, clearly. Keep those ears safe kids from the….peptides.</image:title>
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      <image:caption>July 26, 2025: Thank you to Celestial Beerworks for brewing a tau-inspired IPA to raise awareness and $$$ for Alzheimer’s research at UT Southwestern. Fellow CAND PI, Lukasz Joachimiak, gets credit for the idea and execution. Hopefully, all in the Dallas area will help us drink our way to a cure! Your liver might not thank you, but our Center will! Livers are overrated if the taxpayer invests in NIH liver cures!</image:caption>
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      <image:caption>July 25, 2025: The Labs celebrated the hard work of our Youth Achievers by ending our week at UTSW’s local watering hole, Maple Landing. Beer and mocktails were consumed. Pizza was had. David and Sarah learned way too much about “kids these days” and their Socially Tiktak’ed Internets. Always great to host ambitious and curious local students in the lab! And learn a bit about how old we are!</image:caption>
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      <image:caption>July 25, 2025: Congratulations, Sydnie, for presenting an excellent poster at the Rising Stars Research Symposium! Sydnie shared her summer research on how optogenetic TDP assemblies inefficiently seed TDP fibril formation in cells. A very important contribution to the lab’s first manuscript, which we hope to share soon! Sydnie now leaves to South Dakota for commendable community outreach/service, but we hope she returns to continue her research in the near future!</image:caption>
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      <image:caption>July 25, 2025: Oh….and the lab celebrated David’s very big, but embargoed, funding news at Jose over lunch. More to be shared shortly? Busy day. I’m sure that David’s ego was kept in line.</image:caption>
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      <image:title>News (2025) - July 7, 2025: We are thrilled to announce that former rotation student, Haoxing Liang, has joined the lab as a PhD-seeking graduate student. Haoxing is currently setting up the lab’s first unbiased CRISPR screens!</image:title>
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      <image:caption>July 4, 2025: Happy America Day from all of us in the Shahmoranders group! No fingers were lost—at least on the highly prized pipetting hands of lab members. Fine, David did not check on their “useless” hands. Only need one hand to science! Joking of course :)</image:caption>
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      <image:caption>July 2, 2025: After a humiliating loss to Victor, Grisha decided that his only hope to rehabilitate his reputation was to….wrestle a child. Heck of a job there, Grisha!</image:caption>
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      <image:title>News (2025) - June 30, 2025: Another week, another Shahmorander Youth Achiever unlocked! Welcome Jenny Chu to the lab! She joins us from the most competitive all-girls high school academy in the DFW area. Yeah, that’s right, talking about THE Hockaday School, yo! Jenny will be maximizing the potential of our labs’ computational image analysis pipelines. Her hobbies include writing poetry and outsmarting mean girls! We hate mean girls in the Shahmorander Group!</image:title>
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      <image:title>News (2025) - June 23, 2025: Another Youth Achiever crashed his way thru the UT Southwestern Summer Camp gauntlet to the Shahmoranders group: Ajay Kota, who joins us from beautiful Centennial High in the picturesque suburb of Frisco, TX! Ajay will be working with Victor and Olive on solving cryo-EM structures of cell-extracted tau and TDP-43 fibrils. He will also be defeating Grisha in bi-weekly arm wrestling beat-downs. His WWF idols include THE HULK HOGAN and THE UNDERTAKER. David prefers Orange Cassidy but can’t argue with the greats.</image:title>
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      <image:caption>June 9, 2025: We are delighted that undergraduate extraordinaire, Harper Averitt (left), has returned to the lab from her Baptist studies sabbatical. And we are excited to host UTSW Rising STAR and Youth Achiever, Sydnie Metrano (right). Harper will once again be coordinating with Rupam on our tau-polyserine epic; Sydnie, with Shefali on completing the lab’s first TDP story.</image:caption>
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      <image:caption>May 15, 2025: We were sad to say goodbye to Sarah’s outstanding senior scientist, Tri Tran, who had been leading CLEM efforts in the Lab. We wish him the best of luck on the next stage of his scientific career! He may return one day for a classic Shahmorander twist!</image:caption>
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      <image:caption>May 13, 2025: Thank you to the President’s Research Council at UT Southwestern for funding our research on neuromuscular diseases! It was a pleasure for David to meet so many enthusiastic local backers of UTSW’s research mission….and was certainly humbling to receive so much attention—nice action shot of David with our favorite Dean, Andy Lee! And Marc, sure, sure. Marc’s okay too.</image:caption>
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      <image:title>News (2025) - May 5, 2025: We welcome Haoxing Liang as a rotation student. He will be working with Grisha to cure the TDP…with cats, I assume?</image:title>
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      <image:title>News (2025) - April 8, 2025: It was an honor to meet a hero of the Lab, Jennifer Lippincott-Schwartz, and learn about her latest stunning research on axonal transport. Thank you to Sarah for hosting and for providing an amazing opportunity to learn from one of the great! JLS is a true science rock God! David thanks her specifically for the encouraging words on how to mend fences with his idol who will not be named.</image:title>
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      <image:title>News (2025) - April 4, 2025: The Shamoranders celebrated David’s first “notice of award” at Social Pie—apparently, we invaded a private gathering but whatever! We are funded, ya jabronis, so back off! We are beyond grateful for three-years of funding from the Welch Foundation to support our efforts to understand how polyserine phosphorylation regulates RNA homeostasis.</image:title>
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      <image:caption>March 27, 2025: First rule of Shahmorander Lab Fight Club. Talk about Shahmorander Lab Fight Club. Grisha vs. Victor. Grisha lost…clearly.</image:caption>
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      <image:caption>March 26, 2025: We were delighted to host friend of the Lab, Steven Boeynaems, from Baylor College of Medicine! He gave an excellent talk on how cationic peptides may trigger innate immunity signaling in neurodegenerative diseases! Always a delight to talk crazy ideas with Steven over a drink or two (or more)…with OMAKASE (!!!), clearly :)</image:caption>
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      <image:caption>February 1, 2025: We joined Sarah Shahmoradian’s lab at Community to say goodbye to Valerie Perez, a postdoc with whom David has collaborated over the past 5-years. We wish her the best of luck in her new position at Thermo, where she will be freezing and milling anything they will allow her to!</image:caption>
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